Razib has an essay on the limits of certitude in science, which is saying something coming from a “three cheers for reductionism” type of fellow (which I am also). Meanwhile Andrew Gelman points out some heretics who dare to blaspheme The Great God Randomized Trial. Among them is James Heckman, whom you may have heard about recently.

Le Carrefour de la Sagesse casts some doubt on a theory I was groping toward in an old post. Kudos to him (or her) anyway.

The title of this post stolen in part from Jake Prescott.